Di-µ-bromobis(tri-tert-butylphosphine)dipalladium(I)
化学性质
应用
Coupling reactions. Will activate aryl chloride and sterically hindered or electron rich aryl/vinyl bromides and iodides. Especially active in difficult aminations.Di-µ-bromobis(tri-tert-butylphosphine)dipalladium(I) is used as a catalyst for Suzuki coupling, Negishi coupling and Buchwald-hartwig amination reactions. It is used as a catalyst for C-C, C-N and C-S bond formation, gamma-arylation of alfa,beta-unsaturated esters and diastereoselective arylation of 4-substituted cyclohexyl esters.It is also involved in aromatic halide substitution reactions.
注释
参考文献
Prashad, M.; Mak, X. Y.; Liu, Y.; Repic, O. Palladium-catalyzed amination of aryl bromides with hindered N-alkyl-substituted anilines using a palladium(I) tri-tert-butylphosphine bromide dimer. J. Org. Chem. 2003, 68 (3), 1163-1164.
GHS危险和防护声明
危险说明（欧盟）:H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
防范说明:P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Take off contaminated clothing and wash before reuse. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/ container to an approved waste disposal plant
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书
