4-Chlorobenzylmagnesium chloride, 0.50M in 2-Me-THF
化学性质
应用
4-Chlorobenzylmagnesium chloride is used as an intermediate in organic synthesis. It is used as a precursor for the preparation of 1-chloro-4-(4-methyl-3-pentenyl)benzene by reacting with 1-bromo-3-methyl-2-butene.
注释
参考文献
Eggleston, M. L.; Altundas, R.; Xia, J.; Sikazwe, D. M. N.; Fan, P.; Yang, Q.; Li, S.; Zhang, W.; Zhu, X.; Schmidt, A. W.; Frawley, M. V.; Shrihkande, A.; Villalobos, A.; Borne, R. F.; Ablordeppey, S. Y. Design, Synthesis, and Evaluation of Metabolism-Based Analogues of Haloperidol Incapable of Forming MPP+-like Species. J. Med. Chem. 2004, 47 (3), 497-508.
Lin, L. S.; Lanza, T. J.; Jewell, J. P.; Liu, P.; Shah, S. K.; Qi, H.; Tong, X.; Wang, J.; Xu, S. S.; Fong, T. M.; Shen, C. P.; Lao, J.; Xiao, J. C.; Shearman, L. P.; Stribling, D. S.; Rosko, K.; Strack, A.; Marsh, D. J.; Feng, Y.; Kumar, S.; Samuel, K.; Yin, W.; Ploeg, L. H. T. V.; Goulet, M. T.; Hagmann, W. K. Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity. J. Med. Chem. 2006, 49 (26), 7584-7587.
GHS危险和防护声明
危险说明(欧盟):H225-H302-H313-H314
Highly flammable liquid and vapour. Harmful if swallowed. May be harmful in contact with skin. Causes severe skin burns and eye damage.
防范说明:P242-P264b-P270-P271-P280-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378r-P403+P233-P501c
Use only non-sparking tools. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/ container to an approved waste disposal plant
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书