Lithium bis(trimethylsilyl)amide, 0.9-1.1M in hexane, packaged under Argon in resealable ChemSeal bottles
化学性质
应用
Lithium bis(trimetylsilyl)amide is used as a strong base in organic synthesis and as catalysts in polymerization reactions. It is also used to form various organolithium compounds such as acetylides and lithium enolates. It is a base employed in generating enolates for preparation oflactone precursors, pyranones and cyclohexanes. Further, it is used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines. In addition, it is used in a three-step synthesis of disubstituted 1,2,5-thiadiazoles.
注释
参考文献
Tayama, E.; Toma, Y. Stereoselective preparation of (1Z)-and (1E)-N-Boc-1-amino-1,3-dienes by stereospecific base-promoted 1,4-elimination. Tetrahedron 2015, 71 (4), 554-559.
Lis, A. V.; Tsyrendorzhieva, I. P.; Albanov, A. I.; Shainyan, B. A.; Rakhlin, V. I. Reaction of sodium bis(trimethylsilyl)amide with bromotoluenes. Russ. J. Org. Chem. 2015, 51 (3), 335-340.
GHS危险和防护声明
危险说明（欧盟）:H225-H304-H314-H336-H361-H373-H411
Highly flammable liquid and vapour. May be fatal if swallowed and enters airways. Causes severe skin burns and eye damage. May cause drowsiness or dizziness. Suspected of damaging fertility or the unborn child. May cause damage to organs through prolonged or repeated exposure. Toxic to aquatic life with long lasting effects.
防范说明:P201-P202-P242-P260-P264b-P271-P281-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378r-P403+P233-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use only non-sparking tools. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/ container to an approved waste disposal plant
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书
产品编号公告
