8-Hydroxyquinoline, ACS
化学性质
应用
A bacteriostatic and fungistatic agent. Also a chelating agent for metals.8-Hydroxyquinoline is used as an antiseptic and disinfectant. Its alcoholic solution is used in liquid bandages. It is used to prepare tris(8-hydroxyquinolinato)aluminum, which finds application as a component of organic light-emitting diodes (OLED"s). It is also used as a reagent and as a stabilizer of hydrogen peroxide in a rocket fuel oxidizer. It is used as a chelating agent and used as a carrier for radio-indium for diagnostic purposes. Its halogenated derivatives are used as anti-infective agents and oral antiamebics.
注释
参考文献
Thinnes, C. C.; Tumber, A.; Yapp, C.; Scozzafava, G.; Yeh, T.; Chan, M. C.; Tran, T. A.; Hsu. K.; Tarhonskaya, H.; Walport, L. J.;Wilkins, S. E.; Martinez, E. D.; Müller, S.; Pugh, C. W.; Ratcliffe, P. J.; Brennan, P. E.; Kawamura, A.; Schofield, C. J.Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chem. Commun. 2015, 51 (84), 15458-15461.
Liang, S. H.; Southon, A. G.; Fraser, B. H; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I.; Vasdev, N. Novel fluorinated 8-hydroxyquinoline based metal ionophores for exploring the metal hypothesis of Alzheimers disease. ACS Med. Chem. Lett. 2015, 6 (9), 1025-1029.
GHS危险和防护声明
危险说明（欧盟）:H301-H317-H318-H360-H410
Toxic if swallowed. May cause an allergic skin reaction. Causes serious eye damage. May damage fertility or the unborn child. Very toxic to aquatic life with long lasting effects.
防范说明:P201-P202-P261-P264b-P270-P272-P280g-P302+P352-P305+P351+P338-P310-P330-P363-P405-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/ container to an approved waste disposal plant
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书
