2"-Deoxyguanosine hydrate, 99%
化学性质
应用
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
注释
参考文献
Kasper Broedbaek; Allan Weimann; Elisabeth S. Stovgaard; Henrik E. Poulsen. Urinary 8-oxo-7,8-dihydro-2?-deoxyguanosine as a biomarker in type 2 diabetes. Free Radical Biology and Medicine2011, 51(8), 1473-1479.
Aaron M Fleming; Arunkumar Kannan; James G Muller; Yi Liao; Cynthia J Burrows. Copper/H2O2-mediated oxidation of 2"-deoxyguanosine in the presence of 2-naphthol leads to the formation of two distinct isomeric adducts. Journal of Organic Chemistry,2011, 76 (19), 7953-7963.
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书
