2"-Deoxyuridine, 99%
化学性质
应用
2"-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2?-deoxyuridine include 5-ethynyl-2?-deoxyuridine (DdU) and 5-hydroxymethyl-2?-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples.
注释
参考文献
Brenton L Cavanagh, Tom Walker, Anwar Norazit, Adrian C B Meedeniya. Thymidine analogues for tracking DNA synthesis. Molecules. 2011, 16 (9, 7980-7993.
De Clercq, E., Descamps, J., De Somer, P., Barr, P. J., Jones, A. S., & Walker, R. T.(E)-5-(2-Bromovinyl)-2"-deoxyuridine: a potent and selective anti-herpes agent. Proceedings of the National Academy of Sciences. 1979, 76 (6), 2947-2951.
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书
