Trifluoroacetic acid, biochemical grade, 99.5+%
化学性质
应用
Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis.Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products.It is a precursor to many fluorinated compounds, and widely used in peptide synthesisand other organic transformations involving deprotection of t-BOC group.TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
注释
参考文献
López, S. E.; Salazar, J.Trifluoroacetic acid: Uses and recent applications in organic synthesis. J. Fluorine Chem. 2013, 156, 73-100.
Natu, A. D.; Burde, A. S.; Limaye, R. A.; Paradkar, M. V.Acceleration of the Dakin reaction by trifluoroacetic acid.J. Chem. Res. 2014, 38 (6), 325-386.
GHS危险和防护声明
危险说明（欧盟）:H290-H314-H332-H412
May be corrosive to metals. Causes severe skin burns and eye damage. Harmful if inhaled. Harmful to aquatic life with long lasting effects.
防范说明:P264b-P271-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P390-P402-P403+P233-P406b-P501c
Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Absorb spillage to prevent material damage. Store in a dry place. Store in a well-ventilated place. Keep container tightly closed. Store in corrosive resistant polypropylene container with a resistant inliner Dispose of contents/ container to an approved waste disposal plant
其他参考资料
文件
产品 SDS
质量分析报告(COA)
产品说明书
